Phage therapy: a solution for the expanding antibiotic resistance?

Antimicrobial resistance (AMR) poses a serious global health threat, with 1.27 million deaths in 2019 linked to resistant bacteria. Bacteriophages, viruses that target bacteria, present potential alternatives to antibiotics due to their specificity, self-replicating capability, and lower side effects. However, challenges such as specificity limits and safety concerns remain, prompting ongoing research into phage therapy.

Does mental health first aid training work

University poses significant challenges for students, exacerbated by pandemic effects and rising inequality. Mental health support is inadequate, intensified by socio-economic barriers. While “Mental Health First Aid” courses aim to help, evidence of their effectiveness is lacking. Comprehensive evaluations are necessary before further initiatives are implemented to support student well-being.

The underestimated gut microbiota in gut-brain axis – how do we deal with it?

The human microbiome, comprising diverse microorganisms, significantly impacts health, including digestion and mental well-being. While probiotics and prebiotics show promise, their use should be approached cautiously due to possible risks. Further research on the microbiome’s role and safety of supplements is crucial for understanding its complex influence on health and disease prevention.

Prescription for Pain: America’s Struggle with the Opioid Epidemic

The opioid crisis in America arose from increased prescriptions and misrepresentation by pharmaceutical companies, leading to widespread addiction and overdose deaths. Regulatory failures allowed easy access to addictive drugs, exacerbating the epidemic. Communities, especially those with lower socioeconomic status, suffer disproportionately. Comprehensive interventions are necessary to address disparities and curb the crisis.

Why does it take so long for endometriosis to be diagnosed?

Endometriosis affects over 170 million women globally. Diagnostic delay averages 6.6 years, with extreme cases up to 27 years. Lack of awareness and overlapping symptoms lead to misdiagnosis. Access to private healthcare correlates with shorter diagnostic delays. More research and awareness are needed to reduce the delay and improve patients’ quality of life.

Understanding Multi-System Disorders in Pregnancy

In healthcare settings, women’s pain is often underestimated, affecting perinatal care. Hyperemesis gravidarum (HG) and acute fatty liver of pregnancy (AFLP) are serious but overlooked conditions, impacting women’s health during pregnancy. HG causes severe nausea and vomiting, while AFLP leads to acute liver failure. Understanding these disorders is crucial for improving women’s care.

Infant Institutionalisation: impacts on adulthood

Pavlos Zournatzidis, a UCL PhD student, studies the long-term effects of infant institutionalisation in Greece. His research suggests that early personal connections are vital for healthy emotional and cognitive development. Potential adoption alleviates these effects, underscoring the need for early intervention and increased foster care options to support affected children.

Bridging the Organ Gap: The Promise and Challenges of Xenotransplantation with Pig Organs

Researchers are exploring xenotransplantation, using pig organs to meet the growing demand for organ transplants. Recent breakthroughs include successful pig heart and kidney transplants into humans. Despite concerns about safety and animal welfare, these advances offer hope for addressing the organ shortage crisis. However, further progress and approvals are needed.

Prion Diseases: The Unusual Protein-Misfolding Diseases

Prion diseases are rare and fatal conditions caused by abnormal folding of brain proteins like Creutzfeldt-Jakob disease. Discovered by Prusiner in 1982, these infectious agents induce misfolding in normal proteins, leading to brain damage. Research institutions are studying prion diseases using cerebral organoids and fluorescence detection methods to develop therapies.